Durham is a city in and the county seat of Durham County in the U.S. state of North Carolina.The U.S. Census Bureau estimated the city's population to be 251,893 as of July 1, 2014, making it the 4th-most populous city in North Carolina, and the 78th-most populous city in the United States. Durham is the core of the four-county Durham-Chapel Hill Metropolitan Area, which has a population of 542,710 as of U.S. Census 2014 Population Estimates. The US Office of Management and Budget also includes Durham as a part of the Raleigh-Durham-Chapel Hill Combined Statistical Area, which has a population of 2,037,430 as of U.S. Census 2014 Population Estimates.
It is the home of Duke University and North Carolina Central University, and is also one of the vertices of the Research Triangle area (home of the Research Triangle Park).
The Eno and the Occoneechi, related to the Sioux and the Shakori, lived and farmed in the area which became Durham. They may have established a village named Adshusheer on the site. The Great Indian Trading Path has been traced through Durham, and Native Americans helped to mold the area by establishing settlements and commercial transportation routes.
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